Watch this talk by Caroline Casey. She was born legally blind, but didn't learn that fact until her 17th birthday. She never had the opportunity to use blindness as an excuse. For anything.
You might remember that video I posted a couple of weeks ago about a graffiti artist paralyzed by ALS who is now drawing with his eyes, and showing in galleries.
People all over the world are doing things because they want to, despite limitations many people would use as excuses not to. So it's up to you. Do you ignore limitations, whether personal or societal, or do you continue with "I can't because..."?
Get out there and change. You, the world, it doesn't matter. Make it happen.